Japanese conglomerate Kaneka Corp. has inked an agreement to buy Israeli startup Endostream Medical, a medical device developer for the treatment of brain aneurysms, in a deal valued at about $100 million.

Following the acquisition, the operations of the Or Akiva-based medical device startup will remain in Israel and serve as Kaneka’s research & development center. Kaneka plans to keep Endostream’s 12 employees and hire additional staff to jointly develop devices for the treatment of cerebrovascular diseases that affect the blood flow to the brain, such as aneurysms and strokes.

Founded in 2015 by Danel Mayer, CEO, and Alon May, VP of Technology, Endostream has developed an implant device called Nautilus for the treatment of brain aneurysms. The device has a spiraling design made of nitinol, or nickel titanium, wire covered with a platinum‐based alloy coil sleeve to block and divert blood flow to the aneurysm.

The device, which the startup says has been successfully implanted in hundreds of patients around the world, received regulatory approval in Europe in November 2024. Regulatory approval and........

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