To lead in global innovation, Canada must prioritize basic science

Canada’s National Research Council boldly advertises itself as “advancing mission-driven science and innovation” — to strengthen national security, economic resilience and global competitiveness.

This ambition is difficult to reconcile with a national research system that has, for years, placed too little value on the basic, exploratory, investigator-led science that makes those outcomes possible.

In 2017, Canada’s Fundamental Science Review found that federal funding had shifted too far toward priority-driven and partnership-oriented research. In 2023, the Advisory Panel on the Federal Research Support System made a similar point: mission-driven research depends on the strength of the broader research ecosystem, including curiosity-driven work.

Recent federal investments in research infrastructure, including more than $552 million through the Canada Foundation for Innovation, are important. They help universities, hospitals and research institutions acquire laboratories, equipment and facilities to conduct world-class research.

However, a healthy research ecosystem also needs stable and sustained operating support for investigator-led work. This includes the early, uncertain studies that identify tomorrow’s neglected problems before they become today’s policy priorities.

A nation’s ‘scientific capital’

Health research shows why this distinction matters. We celebrate new treatment advances such as CAR T-cell therapy, which genetically engineers a patient’s immune cells to attack cancer. We welcome CRISPR-based therapies such as Casgevy, a gene-edited cell therapy for sickle cell disease and transfusion-dependent beta-thalassemia.

But these advances did not appear fully formed. They were built through years of work in molecular biology, immunology, genetics,........

© The Conversation