Demi Moore’s emotional acceptance speech on Sunday seemed to jolt awake a sleepy Golden Globes ceremony. Moore’s first win— after three career nominations, including one for “Ghost” back in 1991 — came for female actor in a motion picture musical or comedy for“The Substance.”

The darkly satiric film, written and directed by Coralie Fargeat, has captured something in the moment about women, aging and media, inspiring memes, conversation and countless Halloween costumes. In the film Moore plays Elisabeth Sparkle, an actress turned television fitness guru who is unceremoniously dismissed for being too old. She turns to an underground drug known only as “the substance” to create a........

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