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Approximately 1 in 8 Americans is prescribed a GLP-1 agonist.
GLP-1 agonists have broad utility for treatment of obesity and diabetes, but also may aid with substance use.
Lack of pleasure, drive, and emotional numbness have been reported with GLP-1 use.
Balanced consideration of risks and benefits is necessary as interest in and demand for GLP-1's grows.
The arrival of summer means beach season is calling for many, which may lead some to chase the perfect swimsuit physique. A 2025 Gallup poll showed that 52% of Americans want to lose weight but that only 26% are actively working towards this goal. GLP-1 agents (eg, semaglutide, tirzepatide) are increasingly utilized for weight loss in the United States and are part of patient goals. Despite cost limitations, surveys show that 1 in 8 Americans is currently prescribed a GLP-1........