Fox News senior medical analyst Dr. Marc Siegel discusses the benefits and risks of GLP-1 medications on 'Fox & Friends Weekend.'

Oprah Winfrey is on a tour promoting her new book, "Enough: Your Weight and What It’s Like to Be Free." In 2023, she reportedly had one of her famous "aha" moments, this time realizing her road to personal freedom involved GLP-1 agonist drugs.

She stopped seeing obesity as a personal failure and began viewing GLP-1s as a way to "quiet the noise" that comes with constantly wanting to eat. In her telling, she was suddenly free.

Don’t get me wrong, I believe Oprah’s "aha moments" are real, and I also see the great value of GLP-1 drugs, especially in a society where nearly 70% of the population is either overweight or obese. 

I also like the way these drugs work, decreasing hunger signals in the brain and delaying gastric emptying, which have added benefits that may include reducing the desire for alcohol, improving insulin efficiency and decreasing inflammation in the body. They lower blood pressure, reduce cholesterol levels and improve cardiac function, which is one of the reasons so many cardiologists are taking them. 

OPRAH REVEALS STRUGGLE WITH 'SHAME' OF WEIGHT LOSS DRUGS AND WHAT HAPPENED........

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